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Prog Cell Cycle Res. 2003;5:225-34.

Inhibitors of the CDC25 phosphatases.

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1
Institut Henri Beaufour, Beaufour-Ipsen, 5 Avenue du Canada, Les Ulis 91966, France.

Abstract

As essential cell cycle regulators, the CDC25 phosphatases are currently considered as potential targets for the development of novel therapeutic approaches. Here, we review the function and regulation of CDC25 phosphatases, their involvement in cancer and Alzheimer's disease, and the properties of several recently identified inhibitors.

PMID:
14593717
[Indexed for MEDLINE]
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