Format

Send to

Choose Destination
See comment in PubMed Commons below
Antioxid Redox Signal. 2003 Oct;5(5):557-61.

The free radical theory of aging.

Author information

1
University of Nebraska College of Medicine, Department of Medicine, Omaha, NE 68198-4635, USA.

Abstract

Aging is the accumulation of changes that increase the risk of death. Aging changes can be attributed to development, genetic defects, the environment, disease, and an inborn process: the aging process. The latter is the major risk factor for disease and death after age 28 in the developed countries. In these countries, average life expectancies at birth (ALE-B) now range from 76 to 79 years, 6-9 years less than the limit of approximately 85 years imposed by aging. Aging changes may be caused by free radical reactions. The extensive studies based on this possibility hold promise that the ALE-B can be extended to >85 years and the maximum life span increased.

PMID:
14580310
DOI:
10.1089/152308603770310202
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Mary Ann Liebert, Inc.
    Loading ...
    Support Center