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Semin Cell Biol. 1992 Oct;3(5):301-7.

Small GTP-binding proteins as compartmental markers.

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Unité de Génétique Somatique (URA CNRS 361), Institut Pasteur, Paris, France.


Each intracellular compartment involved in the biosynthetic/secretory pathway of eukaryotic cells bears at its surface at least one small GTP-binding protein. Most of them belong to a distinct branch of the p21ras superfamily, the Sec4/Ypt1/rab family. Other proteins are members of the ARF family. They play a key role in the regulation of budding and targeting/fusion events occurring during protein transport.

[Indexed for MEDLINE]

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