Format

Send to

Choose Destination
See comment in PubMed Commons below
Presse Med. 2003 Oct 18;32(34):1612-7.

[Antipsychotic drugs. Risk factors for diabetes].

[Article in French]

Author information

1
Centre de recherche Fernand-Seguin, Montréal, (Qc). emmanuel.stip@umontreal.ca

Abstract

ANTIPSYCHOTICS AND DIABETES:

After 50 years' use of antipsychotics, it is pertinent to draw-up a circumspect review of the side effects of these psychotropic agents. Moreover, few articles have attempted to elucidate the relationship between the monitoring of carbohydrate metabolism and the prescription of this type of medication.

SEVERAL MECHANISMS AT THE ORIGIN OF AN IMBALANCE IN GLYCAEMIA:

Antipsychotics, notably the atypical forms, represent an additional factor of risk for developing diabetes. The weight gain secondary to this treatment plays an important part in this imbalance, but other mechanisms may also contribute.

DEPENDING ON THE TYPE OF ANTIPSYCHOTIC:

Our present knowledge is insufficient to be able to quantify the effect of each atypical antipsychotic on diabetes. The only tendency that has been reproduced in several studies concerns the increased risk associated with dibenzodiazepine antipsychotics (clozapine and olanzapine), compared with the other antipsychotics.

PMID:
14576587
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center