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Exerc Sport Sci Rev. 2003 Oct;31(4):161-6.

Growth hormone molecular heterogeneity and exercise.

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Military Performance Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760, USA.


There are more than 100 molecular isoforms of circulating growth hormone (GH), but the traditional measurement approach in the exercise literature has only focused on the main isoform (i.e., 22 kDa). New assay methodologies now can assess various GH isoforms. The current data suggest that exercise results in the preferential release of GH isoforms with extended half-lives, thereby sustaining biological actions.

[Indexed for MEDLINE]

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