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[Study on prevention and treatment of radiotherapy caused post-visual pathway injury in nasopharyngeal carcinoma patients by traditional Chinese medicine].

[Article in Chinese]

Author information

1
Department of TCM, Tumor Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou 510060.

Abstract

OBJECTIVE:

To study the effect of TCM in preventing and treating post-visual pathway injury caused by radiotherapy (RT) for nasopharyngeal carcinoma (NPC).

METHODS:

Thirty-five patients of NPC were randomly divided into the RT group (n = 17) and the RT + TCM group (n = 18), they were all received RT, but the latter was treated additionally with Jingming recipe, a Chinese recipe. The latent period and amplitude of evoked potential (EP) were measured before and after ending of RT, using multi-focusing visual evoked potential inspector.

RESULTS:

The latent time of EP, both upper and lower visual field, was prolonged significantly after RT in the RT group (P < 0.05), but not in the RT + TCM group (P > 0.05); the amplitude of EP of upper visual field lowered significantly (P < 0.05) in the RT group but insignificantly in the RT + TCM group (P > 0.05); as for the EP amplitude of lower visual field, it was unaltered in RT group after RT (P > 0.05), but increased in the RT + TCM group (P < 0.05).

CONCLUSION:

The Chinese medicine Jingming recipe was effective in preventing and treating RT induced post-visual pathway injury.

PMID:
14571612
[Indexed for MEDLINE]

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