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Med Decis Making. 2003 Sep-Oct;23(5):435-40.

Validity of standard gamble utilities as measured by transplant readiness in lung transplant candidates.

Author information

1
Department of Medicine, University Health Network, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. lianne.singer@uhn.on.ca

Abstract

PURPOSE:

To evaluate the validity of standard gamble (SG) utilities, by comparing utilities with decision-making behavior in a group of lung transplant candidates facing a risky health decision.

METHODS:

The authors elicited SG utilities for current health from 57 transplant candidates. They assessed the concordance between utility scores and patients' self-reported readiness to be placed on the transplant waiting list ("listed"). Because transplantation represents a real-life gamble with a short-term survival probability of 85%, the authors defined their minimum validity criterion as utility for current health < or = 0.85 in transplant-ready patients.

RESULTS:

Utilities were significantly higher in patients who were not ready for listing (n = 22, median utility = 0.79, range 0.06-1) than in those who were ready or listed (n = 35, median utility = 0.50, range 0-0.85, P < 0.00005). All transplant-ready patients had utilities < or = 0.85 for current health.

CONCLUSIONS:

Low SG utilities were associated with transplant readiness in this population of lung transplant candidates. These results provide one line of evidence supporting the validity of SG utilities as a measure of health-related quality of life, using the criterion of decision-making behavior.

PMID:
14570301
DOI:
10.1177/0272989X03258421
[Indexed for MEDLINE]

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