Abstract
Synthesis and biological activity of 7- and 9-isomers (Z+E) of methylenecyclopropane analogues of 2-aminopurine nucleosides is described. The (S,Z)-9-isomer is a substrate for xanthine oxidase.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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2-Aminopurine / analogs & derivatives*
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2-Aminopurine / chemical synthesis*
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2-Aminopurine / chemistry
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2-Aminopurine / metabolism
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Antiviral Agents / chemical synthesis
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Antiviral Agents / chemistry
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Cyclopropanes
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Indicators and Reagents
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Isomerism
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Substrate Specificity
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Xanthine Oxidase / metabolism
Substances
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Antiviral Agents
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Cyclopropanes
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Indicators and Reagents
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2-Aminopurine
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Xanthine Oxidase