Send to

Choose Destination
Trends Biochem Sci. 1992 Oct;17(10):418-22.

Control of transcription factors by signal transduction pathways: the beginning of the end.

Author information

Department of Pharmacology, University of California, San Diego, School of Medicine, La Jolla 92093-0636.


Signal transduction pathways regulate gene expression by modulating the activity of nuclear transcription factors. The mechanisms that control the activity of two groups of sequence-specific transcription factors, the AP-1 and CREB/ATF proteins, are described. These factors serve as a paradigm explaining the transfer of regulatory information from the cell surface to the nucleus.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center