Format

Send to

Choose Destination
See comment in PubMed Commons below
Curr Med Chem. 2003 Nov;10(21):2253-63.

The chemistry and biochemistry of Spiraea japonica complex.

Author information

1
The State Key Laboratory of Phytochemistry and Plant Resources in West China, Kuming Institute of Botany, Chinese Academy of Sciences, Heilongtan, Kunming, Yunnan 650204, China. haoxj@mail.kib.ac.cn

Abstract

The characteristic components of Spiraea japonica complex, which consists of seven varieties, are the hetisine- and atisine-type diterpene alkaloids, and the atisane-type diterpenes. From this complex, 20 hetisines, 37 atisines and 7 diterpenes were isolated during 1964-2001, including the observations of the isomerization of spiraea diterpene alkaloids having the oxazolidine ring and the interconversion of the oxazolidine rings, the configuration of the oxygen substitution at C-15 of the atisine-type alkaloids, and the interconversion relationship between the two main subtypes of the hetisine-type alkaloids. The chemotaxonomy based on structures of the reported diterpene alkaloids were suggested. The studies on the anti-inflammation, anti-platelet aggregation and neuroprotective bioactivities of the alkaloids from S. japonica var. acuta were reviewed as well.

PMID:
14529341
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Bentham Science Publishers Ltd.
    Loading ...
    Support Center