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Gastrointest Endosc. 2003 Sep;58(3):374-9.

Long-term outcomes for patients with post-liver transplant anastomotic biliary strictures treated by endoscopic stent placement.

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1
Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, USA.

Abstract

BACKGROUND:

Biliary stricture is one of the most common complications of liver transplantation. A number of treatment options are available, but a standard approach has not been established.

METHODS:

A total of 25 patients with post-liver transplantation anastomotic strictures were treated endoscopically by stent placement. Long-term outcomes (bile duct patency, morbidity, and mortality) were reviewed retrospectively.

RESULTS:

Placement of a stent was attempted in 25 patients with anastomotic stricture. Successful stent placement with stricture resolution at the time of stent removal was noted in 22 patients (technical success 88%). In those 22 patients, long-term success (mean follow-up after all stents removed, 54 months) was observed in 20 patients (90%) and partial success in two (10%). Long term, failure did not occur in any patient. There was no procedure- or disease-related mortally. Three mild episodes of cholangitis occurred during the period while the stents were in place, in relation to 79 endoscopic interventions for a procedure-related complication rate of 3.7%.

CONCLUSIONS:

The long-term outcome for patients with post-liver transplantation biliary anastomotic strictures treated with endoscopic stent placement is excellent, with no therapy- or disease-associated mortality and minimal morbidity.

PMID:
14528211
[Indexed for MEDLINE]
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