Apparent deficiency of metallothionein in the liver of the Antarctic icefish Chionodraco hamatus. Identification and isolation of a zinc-containing protein unlike metallothionein

R Scudiero; P Paolo De Prisco; L Camardella; R D'Avino; G di Prisco; E Parisi

doi:10.1016/0305-0491(92)90432-q

Apparent deficiency of metallothionein in the liver of the Antarctic icefish Chionodraco hamatus. Identification and isolation of a zinc-containing protein unlike metallothionein

Comp Biochem Physiol B. 1992 Sep;103(1):201-7. doi: 10.1016/0305-0491(92)90432-q.

Authors

R Scudiero¹, P Paolo De Prisco, L Camardella, R D'Avino, G di Prisco, E Parisi

Affiliation

¹ CNR Institute of Protein Biochemistry and Enzymology, Napoli, Italy.

PMID: 1451431
DOI: 10.1016/0305-0491(92)90432-q

Abstract

1. A zinc-binding protein has been isolated and purified from the liver of the icefish Chionodraco hamatus. 2. The icefish Zn-protein has characteristics distinct from those of metallothionein. 3. The amino acid composition shows a low content of cysteine and a high content of glutamate and aspartate. 4. No metallothionein has been detected in the extracts from icefish liver.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acids / analysis
Animals
Carrier Proteins / chemistry
Carrier Proteins / isolation & purification*
Carrier Proteins / metabolism
Cricetinae
Fishes / metabolism*
Liver / chemistry*
Metallothionein / analysis
Metallothionein / deficiency
Molecular Weight
Rats
Sheep
Species Specificity
Zinc / metabolism*

Substances

Amino Acids
Carrier Proteins
zinc-binding protein
Metallothionein
Zinc