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J Infect Dis. 2003 Oct 1;188(7):1054-8. Epub 2003 Sep 23.

Prevalence and determinants of vaginal flora alterations in postmenopausal women.

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University of Washington School of Medicine, Seattle, Washington, USA.


The vaginal ecology of 463 community-dwelling postmenopausal women was characterized. Vaginal lactobacilli were present in 62% of the women and were significantly more prevalent among women receiving hormone replacement therapy during the previous year. Vaginal Escherichia coli and enterococci were each present in 39% of women and were significantly more frequent in women with a history of urinary tract infection. Heavy growth of lactobacilli was associated with a lower frequency of vaginal colonization with E. coli. Thus, postmenopausal women have a relative depletion of vaginal lactobacilli and an increase in vaginal E. coli compared with premenopausal women.

[Indexed for MEDLINE]

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