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Eur Radiol. 2004 Apr;14(4):686-90. Epub 2003 Sep 26.

Intraoperative functional MRI as a new approach to monitor deep brain stimulation in Parkinson's disease.

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1
Department of Radiology, University of Cologne, Joseph-Stelzmann-Strasse 9, 50924 Cologne, Germany. Volker.Hesselmann@uni-koeln.de

Abstract

This article deals with technical aspects of intraoperative functional magnetic resonance imaging (fMRI) for monitoring the effect of deep brain stimulation (DBS) in a patient with Parkinson's disease. Under motor activation, therapeutic high-frequency stimulation of the subthalamic nucleus was accompanied by an activation decrease in the contralateral primary sensorimotor cortex and the ipsilateral cerebellum. Furthermore, an activation increase in the contralateral basal ganglia and insula region were detected. These findings demonstrate that fMRI constitutes a promising clinical application for investigating brain activity changes induced by DBS.

PMID:
14513267
DOI:
10.1007/s00330-003-2051-0
[Indexed for MEDLINE]
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