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Psychosom Med. 2003 Sep-Oct;65(5):884-8.

Relationship between depression and pancreatic cancer in the general population.

Author information

1
Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA. caroline-carney@uiowa.edu

Abstract

OBJECTIVE:

Prior research suggesting a relationship between pancreatic cancer and depression conducted on clinical populations has been subject to recall bias. We reexamined this association using longitudinal population-based data.

METHODS:

This was a retrospective cohort study using longitudinal insurance claims data.

RESULTS:

Men with mental disorders were more likely to develop pancreatic cancer than those without psychiatric claims (odds ratio 2.4, confidence interval 1.15-4.78). Depression more commonly preceded pancreatic cancer than it did other gastrointestinal malignancies (odds ratio 4.6, confidence interval 1.07-19.4) or all other cancers (odds ratio 4.1, confidence interval 1.05-16.0).

CONCLUSIONS:

Depression and pancreatic cancer are associated in the general population.

PMID:
14508036
[Indexed for MEDLINE]
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