Abstract
Sequences homologous to the human histo-blood group ABO genes are present in the genomic DNA of various mammals. We have PCR-amplified, subcloned, and sequenced a portion of these genes from several species of primates and found high conservation of the nucleotide as well as the deduced amino acid sequences during evolution.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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ABO Blood-Group System / genetics*
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Amino Acid Sequence
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Animals
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Base Sequence
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Biological Evolution*
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Blotting, Southern
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DNA / genetics
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DNA / isolation & purification
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Humans
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Mammals / genetics*
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Molecular Sequence Data
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Oligodeoxyribonucleotides
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Polymerase Chain Reaction / methods
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Primates / genetics*
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Sequence Homology, Amino Acid
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Sequence Homology, Nucleic Acid
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Species Specificity
Substances
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ABO Blood-Group System
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Oligodeoxyribonucleotides
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DNA