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Vopr Virusol. 1992 May-Jun;37(3):153-6.

[The effect of the methods for producing an experimental Marburg virus infection on the characteristics of the course of the disease in green monkeys].

[Article in Russian]


A comparative study on the features of the pathogenesis of Marburg disease after parenteral and aerosol infection of green monkeys with a virus prepared from native culture suspension and that after lyophilization was carried out. The changes in the dynamics of the clotting time, the activity of serum aminotransferases, the duration of prefebrile period and survival time were analysed in different cases. No lethality was observed in animals infected with small doses of aerosol preparations.

[Indexed for MEDLINE]

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