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Vet Rec. 1992 Jul 18;131(3):45-7.

Isolation of Mycobacterium bovis from the respiratory tracts of skin test-negative cattle.

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1
Veterinary Research Laboratories, Stormont, Belfast.

Abstract

Mycobacterium bovis was isolated from the respiratory tracts of three cattle which registered negative to tuberculin testing; no tuberculous lesions were found and the culture of lymph nodes and other tissues proved negative. One animal was from a group of five calves which had been inoculated intranasally with M bovis, and the organism was recovered once only from nasal mucus sampled 100 days after inoculation. The second animal had had contact with experimentally infected cattle which were excreting M bovis and the third was from a commercial farm. The results of ELISAS for antimycobacterial antibodies and interferon-gamma, and of lymphocyte transformation assays are presented. The animals' immune responses provided evidence that each of them had been challenged.

PMID:
1441161
[Indexed for MEDLINE]
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