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Toxicon. 1992 Sep;30(9):1093-8.

Structure determination and toxicity of a new microcystin from Microcystis aeruginosa strain 205.

Author information

1
Department of Pharmacy, University of Helsinki, Finland.

Abstract

A new hepatotoxic microcystin was isolated from the cyanobacterium Microcystis aeruginosa strain 205. Its structure was found to be [Dha7]microcystin-RR as determined by amino acid analysis, mass spectrometry and 1H NMR spectroscopy. LD50 value (i.p. mouse) of this toxin was 180 micrograms/kg. The 48 hr lethal concentration (48-hr-LC50) of the toxin for larvae of the yellow fever mosquito, Aedes aegypti, was 14.9 micrograms/ml.

PMID:
1440646
DOI:
10.1016/0041-0101(92)90054-9
[Indexed for MEDLINE]

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