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Nature. 1992 Nov 5;360(6399):33-9.

Stabilization of sea urchin flagellar microtubules by histone H1.

Author information

1
Département de Biologie Moléculaire et Structurale, Unité INSERM 244, Grenoble, France.

Abstract

Complex microtubule assemblies are essential components of eukaryotic cilia and flagella. They are extremely stable and are not affected by agents that normally induce polymer disassembly. The molecular basis of this microtubular stability is unknown, and it is not related to any feature of the constitutive tubulin. In sea urchin sperm flagella, axonemal microtubules are found to be stabilized by a protein identical to histone H1, a result that defines a new role for this histone and provides evidence for a concerted evolution of chromatin and microtubular structures.

PMID:
1436071
DOI:
10.1038/360033a0
[Indexed for MEDLINE]

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