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Fertil Steril. 1992 Nov;58(5):1034-9.

Effect of ascorbic acid supplementation on the sperm quality of smokers.

Author information

1
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston 77555.

Abstract

OBJECTIVE:

To determine the effect of ascorbic acid supplementation on the sperm quality of heavy smokers.

DESIGN:

Microscopic examination of semen for 1 month during supplementation with placebo or ascorbic acid at dose levels of 200 or 1,000 mg/d.

SETTING:

Department of Obstetrics and Gynecology, The University of Texas Medical Branch.

PARTICIPANTS:

Seventy-five men (20 to 35 years old) randomly divided into one of three supplementation groups: placebo, 200 mg and 1,000 mg of ascorbic acid.

MAIN OUTCOME:

Improvement in sperm quality as compared with presupplementation levels and between the three treatment groups.

RESULTS:

The placebo group showed no improvement in sperm quality. The groups receiving ascorbic acid showed improvement in sperm quality with most improvement in the 1,000-mg group. Pearson's correlation showed statistically significant relationships between the weekly group means of serum and seminal plasma ascorbic acid levels and sperm qualities.

CONCLUSIONS:

Ascorbic acid supplementation of heavy smokers in excess of 200 mg/d results in improved sperm quality.

PMID:
1426355
[Indexed for MEDLINE]

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