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Cancer Genet Cytogenet. 1992 Oct 1;63(1):22-4.

Trisomy 7 in nonneoplastic focal steatosis of the liver.

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  • 1Department of Clinical Genetics, Lund University Hospital, Sweden.


Cytogenetic analysis of short-term cultures of a nonneoplastic focal steatosis of the liver showed trisomy 7 as the sole chromosomal change. This finding, especially when viewed in light of previous reports describing +7 in nonneoplastic tissues, strongly suggests that trisomy 7 cannot be considered a tumor-specific abnormality when it occurs as the only change. The cell type in which +7 is present is not yet known.

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