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Biull Eksp Biol Med. 1992 May;113(5):506-8.

[Participation of protein synthesis in brain cell structures in the action of antifeins on long-term memory].

[Article in Russian]

Abstract

Incorporation of 3H-leucine into proteins of rat brain cell structures during application of antifeins (compounds of alternative action on memory processes) has been studied. No correlation was observed between changes in protein synthesis in nuclei, mitochondria, components of endoplasmic reticulum and memory effects of ethyl-, allyl- and propylnorantifeins. Only M1 and M2-demethylated structural analogs of ethylnorantifeins (exerting the most effective action on RNA synthesis and retention of conditional reflexes) enhanced the synaptosomal protein synthesis.

PMID:
1421271
[Indexed for MEDLINE]

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