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Semin Cell Biol. 1992 Aug;3(4):255-66.

An extended view of nuclear lamin structure, function, and dynamics.

Author information

1
Howard Hughes Medical Institute, University of California, San Francisco 94143-0554.

Abstract

Molecularly-based studies of nuclear lamins have progressed at a rapid rate in the last decade. However, we still have no answer to the most important question: what are the functions of lamins? In this review we describe recent experiments which challenge traditional views of lamin function and structure. These surprising results indicate that much lamin functionality remains to be discovered, and that more global approaches to lamin structure and function are especially appropriate at this time.

PMID:
1421171
DOI:
10.1016/1043-4682(92)90027-s
[Indexed for MEDLINE]

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