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Science. 1964 May 15;144(3620):844-6.

SPLEEN-COLONY FORMATION IN ANEMIC MICE OF GENOTYPE WW.

Abstract

The hemopoietic cells from anemic mice of genotype WW are less able by 200-fold to take part in colony formationin the spleen than cells from the normal littermates of genotype ww. The genetic defect shows itself in the colony-forming cells, since cells from normal littermate mice formcolonies in the spleens of unirradiated mice of genotype WW. Use of animals of genotype WVVWT as recipients improves the spleen-colony method by removing bias resulting fromthe death of irradiated recipients.

PMID:
14149394
[Indexed for MEDLINE]
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