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Yao Xue Xue Bao. 1992;27(3):173-7.

[Studies on the alkaloids of Cephalotaxus. VII. Structures and semi-synthesis of two anticancer cephalotaxine esters].

[Article in Chinese]

Author information

1
Shanghai Institute of Materia Medica, Academia Sinica.

Abstract

Two new alkaloids, namely neoharringtonine (1) and anhydroharringtonine (2) with significant antileukemic activity were isolated from Cephalotaxus fortunei Hook f.. Their structures have been established by spectral analyses and semi-synthesis. Seven known alkaloids, deoxyharringtonine (3), isoharringtonine (4), isocephalotaxinone (5), acetylcephalotaxine (6), cephalotaxine (7), harringtonine (8) and homoharringtonine (9), were also isolated and identified.

PMID:
1414381
[Indexed for MEDLINE]
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