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OBSERVATIONS ON THE RESISTANCE IN HB E THALASSAEMIA DISEASE TO INDUCED INFECTION WITH PLASMODIUM VIVAX.

Abstract

Subjects with sickle cell trait have been known to offer resistance to induced Plasmodium falciparum infection. The resistance to malarial infection in other haemoglobinopathic disorders is not clearly known. Investigations were undertaken to test for resistance to malaria in Hb E thalassaemia disease. Compared to controls, subjects with Hb E thalassaemia disease were found to have significant resistance to induced Plasmodium vivax infection.

PMID:
14122440
PMCID:
PMC2554904
[Indexed for MEDLINE]
Free PMC Article

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