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Science. 1964 Jan 24;143(3604):371-3.

OXIDATION OF CARBON-14-LABELED ENDOGENOUS LIPIDS BY ISOLATED PERFUSED RAT HEART.

Abstract

Lipids of the rat heart were labeled with carbon-14 in vivo. The production of C(14)O(2) during the subsequent perfusion of these glycogen-depleted hearts with buffer, but without added substrate, provided direct evidence of the oxidation of endogenous heart lipids. The net decrease in phospholipid content alone could account for 75 percent of the total metabolic CO(2) formed.

PMID:
14074856
[Indexed for MEDLINE]

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