Format

Send to

Choose Destination
Zhonghua Zhong Liu Za Zhi. 1992 Jul;14(4):270-2.

[Action of calmodulin antagonist on the proliferation and cytoskeleton of A549 lung cancer cells].

[Article in Chinese]

Author information

1
Hubei Medical College, Wuhan.

Abstract

Trifluoperazine (TFP) could inhibit the proliferation of A549 lung cancer cells and human embryo lung (HEL) cells. The inhibitory effects were dose dependent. The inhibitory effects were stronger in A549 lung cancer cells than in HEL cells at the same TFP dose. Cytoskeleton in A549 lung cancer cells treated with TFP was increased as observed electron microscopically. The role of calmodulin in the proliferation and the changes in cytoskeleton of A549 lung cancer cells is discussed.

PMID:
1396074
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center