Format

Send to

Choose Destination
Clin Neuropharmacol. 1992 Jun;15(3):186-228.

The neurobiology of the opsoclonus-myoclonus syndrome.

Author information

1
Department of Neurology, George Washington University, Washington, DC.

Abstract

Opsoclonus-myoclonus is a pervasive neurological syndrome of children and adults. Although rare, it raises important clinical and neurobiological issues. This article provides an overview of the clinical and laboratory features, differential diagnosis, treatment, and outcome of opsoclonus-myoclonus. It pursues immunologic, genetic, electrophysiologic, neurochemical, and other clues to a pharmacologic model. Key questions include how and where the brain is injured, reversibility of the injury, possible targets for pharmacologic intervention, and which new studies are needed.

PMID:
1394242
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center