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Curr Opin Genet Dev. 1992 Aug;2(4):562-6.

The role of Wnt genes in vertebrate development.

Author information

1
Roche Institute of Molecular Biology, Department of Cell and Developmental Biology, Nutley, New Jersey 07110.

Abstract

Over the past decade, many potential candidates for molecules involved in pattern formation in the vertebrate embryo have been identified. Manipulation of the expression of some of these factors has generated fascinating results that have allowed investigators to address their roles in embryogenesis. One such family consists of a group of putative cell signaling molecules related to the proto-oncogene Wnt-1. An accumulating body of evidence suggests that the Wnt-family plays a major role in several aspects of vertebrate development.

PMID:
1388080
DOI:
10.1016/s0959-437x(05)80172-8
[Indexed for MEDLINE]

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