Format

Send to

Choose Destination
FEBS Lett. 1992 May 11;302(2):172-6.

Cloning and sequencing of the 23 kDa mouse photoreceptor cell-specific protein.

Author information

1
Department of Anatomy and Cell Biology, University of California, Los Angeles 90024.

Abstract

The 23 kDa protein was localized by immunocytochemistry to photoreceptor cells of the mouse retina, and bovine and mouse cDNA clones were isolated and sequenced. The deduced amino acid sequences showed that the mouse 23 kDa protein is 91% identical to the bovine protein, and is the same as S-modulin, the CAR (cancer-associated retinopathy) protein and recoverin, the Ca(2+)-dependent activator of photoreceptor guanylate cyclase. The amino acid sequence reveals two Ca2+ binding sites, no internal repeats, 59% homology to the chicken visinin protein and 40% homology to calmodulin while Northern analysis demonstrated a single 1.0 kb mRNA species in bovine and mouse retina.

PMID:
1386025
DOI:
10.1016/0014-5793(92)80433-h
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center