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Eur Urol. 1992;22(1):64-9.

The 'female prostate': location, morphology, immunohistochemical characteristics and significance.

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Institute of Pathology, University of the Saarland, Homburg/Saar, FRG.


Using immunostaining for prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP), we can demonstrate prostate-analogous periurethral glands (the 'female prostate') in 66.7% of 33 cases. Histomorphologically, these glands resemble strongly the male prostate glands before puberty. They remain immature throughout life from the fetal period up to advanced age obviously because of a lack of an androgenic stimulus. The glands have long ducts leading into the urethra. A proper stroma component is missing. The immunohistochemical behavior of these glands also corresponds widely to that of the male prostate glands before puberty. No indications can be found for a proper biological function.

[Indexed for MEDLINE]

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