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Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8948-52.

Spatial pattern of receptor expression in the olfactory epithelium.

Author information

1
Laboratory for Molecular Neurobiology, Salk Institute, La Jolla, CA 92186-5800.

Abstract

A PCR-based strategy for amplifying putative receptors involved in murine olfaction was employed to isolate a member (OR3) of the seven-transmembrane-domain receptor superfamily. During development, the first cells that express OR3 appear adjacent to the wall of the telencephalic vesicle at embryonic day 10. The OR3 receptor is uniquely expressed in a subset of olfactory cells that have a characteristic bilateral symmetry in the adult olfactory epithelium. This receptor and its specific pattern of expression may serve a functional role in odor coding or, alternatively, may play a role in the development of the olfactory system.

PMID:
1384038
PMCID:
PMC50041
DOI:
10.1073/pnas.89.19.8948
[Indexed for MEDLINE]
Free PMC Article

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