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Immunol Today. 1992 Aug;13(8):300-6.

Allorecognition by NK cells: nonself or no self?

Author information

1
Dip. di Medicina ed Oncologia Sperimentale, University of Turin, Italy.

Abstract

The issue of antigen recognition by NK cells is complex, fascinating and, as yet, unresolved. This article reviews recent research on the repertoire of human NK cell clones for the recognition of different allogeneic cells, and summarizes the studies, most of which have been performed in mice, that implicate the MHC in NK cell recognition. It goes on to provide a common conceptual framework within which these different systems may be understood.

PMID:
1380815
DOI:
10.1016/0167-5699(92)90042-6
[Indexed for MEDLINE]

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