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FEBS Lett. 1992 Jun 1;303(2-3):210-2.

Bleomycin-detectable iron in the plasma of premature and full-term neonates.

Author information

1
Department of Biochemistry, Kings College, London, UK.

Abstract

The bleomycin assay measures non-transferrin-bound iron, able to catalyze free radical reactions, in human plasma. No bleomycin-detectable iron is present in plasma from healthy adults. However, plasma from 3/15 premature babies was positive in this assay. Plasma from 52 apparently-healthy term babies was analyzed and 11 were positive in the bleomycin assay. Hence not only some premature but also some full-term apparently-healthy babies may be at risk of severe oxidative damage.

PMID:
1376697
DOI:
10.1016/0014-5793(92)80521-h
[Indexed for MEDLINE]
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