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Appl Microbiol Biotechnol. 2003 Dec;63(2):115-27. Epub 2003 Sep 16.

Bacterial heme biosynthesis and its biotechnological application.

Author information

1
Institute for Microbiology, Technical University of Braunschweig, Spielmannstrasse 7, 38106, Braunschweig, Germany. n.frankenberg@tu-bs.de

Abstract

Proteins carrying a prosthetic heme group are vital parts of bacterial energy conserving and stress response systems. They also mediate complex enzymatic reactions and regulatory processes. Here, we review the multistep biosynthetic pathway of heme formation including the enzymes involved and reaction mechanisms. Potential biotechnological implications are discussed.

PMID:
13680202
DOI:
10.1007/s00253-003-1432-2
[Indexed for MEDLINE]

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