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Cell. 2003 Sep 5;114(5):537-43.

Cryptochromes: enabling plants and animals to determine circadian time.

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Plant Science Institute, Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.


Cryptochromes are flavin-containing blue light photoreceptors related to photolyases-they are found in both plants and animals and have recently been described for bacteria. In plants, cryptochromes perform a variety of functions including the entrainment of circadian rhythms. They serve a similar role in Drosophila and mammals, where the cryptochromes also perform an additional function as an essential component of the circadian clock.

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