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Curr Opin Biotechnol. 1991 Aug;2(4):582-91.

Metal-binding sites in proteins.

Author information

1
Department of Molecular Biology, Scripps Research Institute, La Jolla, California 92037.

Abstract

A dramatic increase in the number of solved metalloprotein structures and recent breakthroughs in structural analysis have provided a sufficiently detailed understanding of the structural chemistry of some metal-binding sites to allow successful design. As a result, metal-binding site design is now one of the most powerful and promising approaches for influencing protein folding, assembly, stability and catalysis.

PMID:
1367679
DOI:
10.1016/0958-1669(91)90084-i
[Indexed for MEDLINE]

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