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Adv Exp Med Biol. 1992;327:255-62.

Immunization with fimbrial protein and peptide protects against Porphyromonas gingivalis-induced periodontal tissue destruction.

Author information

1
School of Dental Medicine, Department of Oral Biology, State University of New York, Buffalo 14214.

Abstract

In these studies we have attempted to show that cell surface structures are critical antigens for protection against P. gingivalis-induced periodontal destruction. Fimbrillin, and in particular a synthetic 20-amino-acid fimbrillin peptide, exerts a protective effect in gnotobiotic rats, thus identifying them as potentially useful in the development of a vaccine.

PMID:
1363504
DOI:
10.1007/978-1-4615-3410-5_27
[Indexed for MEDLINE]

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