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Muscle Nerve. 1992 Nov;15(11):1234-9.

Demyelinating peripheral neuropathy in Creutzfeldt-Jakob disease.

Author information

1
Department of Neurology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Israel.

Abstract

We describe 2 patients of Jewish Libyan descent, who presented with a clinical syndrome compatible with Creutzfeldt-Jakob disease and who were found to have a mutation of codon 200 in the prion protein. The patients developed symptoms and signs of peripheral nerve involvement diagnosed by electrodiagnostic and histopathological studies as demyelinating neuropathy. This may be a rare manifestation of Creutzfeldt-Jakob disease.

PMID:
1362595
DOI:
10.1002/mus.880151103
[Indexed for MEDLINE]

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