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Infection. 1992 Sep-Oct;20(5):263-6.

Pulmonary involvement in nephropathia epidemica as demonstrated by computed tomography.

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Dept. of Infectious Diseases, University of Umeå, Sweden.


In a prospective study 19 adult patients with nephropathia epidemica were examined in the acute phase of disease with computed tomography (CT) of the lungs and conventional chest radiography. Infiltrates and/or pleural effusions were seen in ten of 19 patients. In two of the patients, abnormalities were disclosed only by CT. Patients with pathologic radiography findings had a more pronounced inflammatory response, as measured by C-reactive protein and leukocyte count, than did those with normal radiography findings. It is concluded that radiological evidence of pulmonary involvement is a common finding early in the course of nephropathia epidemica. The possibility that the lung may be a site of viral replication merits further investigation.

[Indexed for MEDLINE]

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