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J Psychiatry Neurosci. 1992 Mar;17(1):23-7.

Cerebrospinal fluid concentrations of neuropeptide Y in depressed patients and in controls.

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1
Sct. Hans Hospital, Dept. P & Research Institute of Biological Psychiatry, Roskilde, Denmark.

Abstract

Concentrations of Neuropeptide Y-like (NPY-LI) immunoreactivity in cerebrospinal fluid (CSF) were measured in a group of depressed patients (n = 24) and compared with that of control subjects (n = 12). CSF-NPY-LI was significantly reduced in the group of non-endogenously depressed patients when classified according to Newcastle Rating Scale for Depression--1971 (N-II). No significant correlation was found in the control or depressed groups between lumbar concentrations of NPY-LI and a number of other neurotransmitters.

PMID:
1349825
PMCID:
PMC1188381
[Indexed for MEDLINE]
Free PMC Article
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