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Rev Pneumol Clin. 1992;48(6):269-74.

[Malignant primary intrathoracic histiocytofibroma].

[Article in French]

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Hôpital d'Instruction des Armées D. Larrey, Service de Pneumologie, Versailles.


Malignant primary intrathoracic fibrous histiocytoma (MFH) is a rare tumour: since it was first described in 1979, hardly more than 80 cases have been published. We present a large MFH which had started in the pleura and was intrathoracic. The tumour was typical, being comprised of malignant fibroblastic and histiocytoid cells in storiform arrangement. It was revealed by spinal bone metastases which multiplied over the whole skeleton in spite of chemotherapy. The patient died of cerebral metastasis developed 8 months after the onset of the disease. The cases found in the literature are gathered together and commented.

[Indexed for MEDLINE]

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