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Curr Opin Neurol Neurosurg. 1992 Dec;5(6):924-31.

Histological grading of gliomas.

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Service d'Anatomie Pathologique, Centre Hospitalier Sainte-Anne, Paris, France.


Usefulness of grading systems based on non-specific features (e.g. mitosis, necrosis) is unequivocal in only certain types of astrocytomas, and their efficiency remains to be seen in oligodendrogliomas and in mixed oligo-astrocytomas. The possibility of grading ependymomas is still uncertain. Accordingly, only a small proportion of gliomas which occur in children can be reliably graded. Lack of reproducibility is a severe impediment of both current conventional and kinetic methods in the prognosis of gliomas.

[Indexed for MEDLINE]

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