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Oncogene. 1992 Dec;7(12):2529-34.

Physical mapping of human loci homologous to the chicken nov proto-oncogene.

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Laboratoire d'Oncologie Virale et Mol├ęculaire, Institut Curie, Orsay, France.


The human locus (novH) corresponding to the nov protooncogene overexpressed in avian nephroblastoma has been identified and mapped on chromosome 8q24.1. Another locus sharing homology with novH and corresponding to the connective tissue growth factor (CTGF) gene has also been mapped on chromosome 6q23.1. The chromosomal assignment of nov and CTGF proximal to c-myc and c-myb respectively is of interest because chromosomal abnormalities involving these regions have been associated with different human tumors including Wilms'.

[Indexed for MEDLINE]

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