Melanotic neuroectodermal tumor of the skull and meninges in infancy

Pediatr Neurosurg. 1992;18(1):6-15. doi: 10.1159/000120636.

Abstract

Three cases of melanotic neuroectodermal tumors of infancy are presented. Two were localized on the midline, involving the skull and extending subdurally. One was located on the inner aspect of the dura and developed intracranially. Two had a benign course following gross total removal. One had a malignant course, recurring locally and spreading within the brain. The difficulties of removing these tumors when they are implanted on the midline are stressed. Histological features of prognostic value are pointed out. Further support for neural crest origin of these tumors is given.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Craniotomy
  • Female
  • Follow-Up Studies
  • Frontal Bone / diagnostic imaging
  • Frontal Bone / pathology
  • Frontal Bone / surgery*
  • Humans
  • Infant
  • Meningeal Neoplasms / diagnostic imaging
  • Meningeal Neoplasms / pathology
  • Meningeal Neoplasms / surgery*
  • Meninges / pathology
  • Microscopy, Electron
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery
  • Neoplasm Seeding
  • Neoplasms, Germ Cell and Embryonal / diagnostic imaging
  • Neoplasms, Germ Cell and Embryonal / pathology
  • Neoplasms, Germ Cell and Embryonal / surgery*
  • Parietal Bone / diagnostic imaging
  • Parietal Bone / pathology
  • Parietal Bone / surgery*
  • Reoperation
  • Skull Neoplasms / diagnostic imaging
  • Skull Neoplasms / pathology
  • Skull Neoplasms / surgery*
  • Tomography, X-Ray Computed