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Curr Opin Cell Biol. 1992 Oct;4(5):869-74.

Agrin isoforms and their role in synaptogenesis.

Author information

1
Department of Neurobiology, Stanford University School of Medicine, California 94305-5401.

Abstract

Agrin is thought to mediate the motor neuron-induced aggregation of synaptic proteins on the surface of muscle fibers at neuromuscular junctions. Recent experiments provide direct evidence in support of this hypothesis, reveal the nature of agrin immunoreactivity at sites other than neuromuscular junctions, and have resulted in findings that are consistent with the possibility that agrin plays a role in synaptogenesis throughout the nervous system.

PMID:
1329871
DOI:
10.1016/0955-0674(92)90113-q
[Indexed for MEDLINE]

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