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Trends Biochem Sci. 1992 Mar;17(3):100-4.

Engineered metalloregulation in enzymes.

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  • 1Department of Pharmaceutical Chemistry, University of California, San Francisco 94143.

Abstract

Protein engineering of metal-dependent enzyme activity is now possible due to the wealth of information available about metalloproteins. The results emerging from these studies provide insight into our understanding of the chemistry of metals in macromolecular environments as well as the biology of metal-protein interactions.

PMID:
1329276
[PubMed - indexed for MEDLINE]
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