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J Pediatr. 1992 Oct;121(4):622-5.

Alpha-adrenergic bronchoprovocation in neonates with bronchopulmonary dysplasia.

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1
Section on Newborn Pediatrics, Pennsylvania Hospital.

Abstract

Ophthalmic administration of phenylephrine caused decreased pulmonary compliance, tidal volume, and peak airflow values in infants with bronchopulmonary dysplasia but not in control infants. The alpha-adrenergic effects of phenylephrine may aggravate the bronchospastic component of bronchopulmonary dysplasia.

PMID:
1328578
[Indexed for MEDLINE]

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